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DOI: 10.24075/dc.2026.011
Copyright: © 2026 by the authors. Licensee: Pirogov University.
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (CC BY).

ORIGINAL RESEARCH

The structure and biological potential of substituted uracil-propanesultone derivatives: from tautomeric preferences to drug design

Gusev RA1 , Kramarova EP1 , Volchenkov TI1 , Korlyukov AA2 , Lagunin AA1 , Baukov YuI1 , Shmigol TA1 , Negrebetsky VV1
About authors

1 Pirogov Russian National Research Medical University, Moscow, Russia

2 Nesmeyanov Institute of Organoelement Compounds of the Russian Academy of Sciences, Moscow, Russia

Correspondence should be addressed: Vadim V. Negrebetsky
Ostrovityanova Str., 1, Moscow, 117513, Russia; ur.umsr@1ykstebergen

About paper

Author contribution: Gusev RA — performing QSAR analysis, preparation of the manuscript; Kramarova EP — preparation of the manuscript; Volchenkov TI — performing QSAR analysis; Korlyukov AA — quantum-chemical calculations, preparation of the manuscript; Lagunin AA — performing QSAR analysis, preparation of the manuscript; Baukov YI — academic advising; Shmigol TA — biological part, preparation of the manuscript; Negrebetsky VV — formulation of the study goal, preparation of the manuscript; all authors contributed equally to the preparation of the manuscript; they confirm that their contribution complies with the international criteria of ICMJE.

Received: 2026-05-29 Accepted: 2026-06-10 Published online: 2026-06-16
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